Werner syndrome RecQ helicase-IN-1

CAS No. 2869954-34-5

Werner syndrome RecQ helicase-IN-1( —— )

Catalog No. M36443 CAS No. 2869954-34-5

Werner syndrome RecQ helicase-IN-1 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 84 Get Quote
5MG 121 Get Quote
10MG 177 Get Quote
25MG 287 Get Quote
50MG 486 Get Quote
100MG 761 Get Quote
500MG 1701 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Werner syndrome RecQ helicase-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Werner syndrome RecQ helicase-IN-1 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.
  • Description
    Werner syndrome RecQ helicase-IN-1 (example 42) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research.
  • In Vitro
    Werner syndrome RecQ helicase-IN-1 (example 42) has an IC50 value of 100 nM for WRN ATPase and GI50 values of 50 nM and >10 μM for SW48 and DLD1 WRN-KO cell lines, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2869954-34-5
  • Formula Weight
    702.08
  • Molecular Formula
    C31H31ClF3N9O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (142.43 mM; Ultrasonic )
  • SMILES
    C(C(NC1=C(Cl)C=C(C(F)(F)F)C=C1)=O)N2C=3N(C(=O)C(=C2CC)N4CCN(C(=O)C=5C(O)=C(C)N=CN5)CC4)N=C(N3)C=6CCOCC6
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Triazolo-pyrimidine analogues for treating diseases connected to the inhibiton of werner syndrome recq helicase (wrn). WO2022249060
molnova catalog
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